Non-invasive testing

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Non-invasive prenatal testing.

BACKGROUND Non-invasive prenatal testing (NIPT), also known as cell-free DNA testing and non-invasive prenatal screening (NIPS), is an important addition to the range of screening tests for fetal chromosomal abnormalities. For trisomy 21 in particular, NIPT is superior to other screening modalities. However, NIPT has limitations and complexities that requesting clinicians and their patients sho...

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Uveal Melanoma: Non-Invasive Predictive Testing

Uveal melanoma (UM) is the most common intraocular tumor in the western population. Overall survival has not improved during the past decades, despite a shift towards more conservative eye treatments. 1 Currently, the choice of treatment for UM depends on size and location of the tumor, secondary effects of the tumor on the eye (for instance inflammation or neovascular glaucoma), the status of ...

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Cord Blood Karyotyping: A Safe and Non-Invasive Method for Postnatal Testing of Assisted Reproductive Technology Children

Objective To verify the hypothesis that the incidence of chromosomal abnormalities increases in babies conceived by different assisted reproduction procedures. The availability of the umbilical cord blood encouraged us to study this hypothesis via this method. MaterialsAndMethods This is a descriptive study, umbilical cord blood samples of assisted reproductive technology (ART) children were an...

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Aneuploidy screening by non‐invasive prenatal testing in twin pregnancy

OBJECTIVES To describe our experience with non-invasive prenatal testing (NIPT) in twin pregnancy. METHODS Two sets of maternal blood samples from twin pregnancies were analyzed at our laboratory using NIPT: 115 stored samples from pregnancies with known outcome (Clinical Study A) and 487 prospectively collected samples for which outcomes were requested from providers (Clinical Study B). NIPT...

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Diabetomics : ProsPects for NoN-iNvasive Diabetes testiNg aND DiagNosis

the twin epidemics of obesity and diabetes threaten to overwhelm healthcare systems in the U.s. and worldwide (1). a major challenge in dealing with the burden of diabetes is our inability to easily and conveniently detect diabetes and prediabetes in at-risk populations due to the lack of a non-invasive, point-of-care test. as discussed below, body fluids such as saliva and urine constitute a r...

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ژورنال

عنوان ژورنال: British Dental Journal

سال: 2010

ISSN: 0007-0610,1476-5373

DOI: 10.1038/sj.bdj.2010.4